LS² Annual Meeting 2016

Interdisciplinary Sciences

15–16 February, 2016
Amphimax/Amphipôle, Lausanne

Flyer of the meeting

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Final meeting program

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Careers in Science

Meet the discussion leaders of the lunch session "Careers in Science" and decide whom you would like to talk to...

The discussion session is split into three separate rooms: "Junior careers in academia", "Senior careers in academia" and "Non-academic careers".


09:00 – 09:10

Welcome Address

Aurélien Roux, meeting chairman (University of Geneva)

Thierry Soldati (President of LS2)

09:10 – 10:00

Plenary Lecture I


Lakshminarayanan MAHADEVAN

Harvard University, Department of Physics, Cambridge, USA

➤ Visit Mahadevan's Lab Page


Towards a physical basis for morphogenesis

10:00 – 10:30


10:30 – 12:30

Parallel Symposia I


Molecular and Cellular Biosciences

Unravelling novel paradigms in biology using model organisms


Ramesh S. Pillai (EMBL Grenoble)

Genome defense by germline small RNAs


Michael O'Connor (University of Minnesota)

Vesicle-mediated steroid hormone secretion in Drosophila melanogaster


Rohit Chavan (University of Fribourg)

Liver-derived ketone bodies are necessary for food anticipation


Ewald Collins (Harvard Medical School) 

Reduced insulin/IGF-1-signalling implicates extracellular matrix remodelling in longevity


Malathi Raman (TAKARA Clontech)

Change the way you think about Cloning….Discover In-Fusion®




Plant Sciences

Plant Molecular and Chemical Biology


Dorothea Tholl (Virginia Tech University)

How plant scent makes sense: Studies in Arabidopsis and beyond


Jurriaan Ton (University of Sheffield)

Onset and long-term maintenance of plant immune priming


Cornelia Eisenach (University of Zurich)

Identification of a vacuolar malate channel required for plant water balance


Maite Colinas (University of Geneva)

Balancing of B6 vitamers is essential for plant development and metabolism in Arabidopsis


David Heywood (Waters)

Effects of Light Exposure on the Lipid Metabolism of Broccoli Sprouts: An Untargeted, Unbiased Metabolomics Approach



Microbial division and replication: from biochemistry to molecular biology


Patrick Viollier (University of Geneva)
The chlamydial division septum: organisation and regulation


Beate Henrichfreise (University of Bonn)
Importance of amidases and peptidoglycan in chlamydial division


Ioan Iacovache (University of Bern)

Near-atomic structure of aerolysin mutants reveals a novel protein fold and elucidates its mode of action


 Joe Dan Dunn (University of Geneva)

Delineating the immunity functions of reactive oxygen species using Dictyostelium discoideum as a model phagocyte


Sophie Martin (University of Lausanne)
Spatio-temporal control of cell division in fission yeast


Special Session

MSc- what's next?


In this session directed at young scientists at the beginning of their career, you can gather information on your career opportunities after having finished with the Master. Several life sciences alumni who have kickstarted their career in Academia, the industry, and non-for profit organisations will answer all your questions in one-to-one discussions. 

12:30 – 13:40


Posters with even numbers are accompanied by the presenter

12:40 – 13:30

Careers of women and men in Science

Round table discussion

The lunch session "Careers of women and men in Science" is aimed at providing career support to young researchers at any stage, with a special focus on dual career couples, and women-specific mentoring and fellowships in the life sciences. Several round tables with at least one mentor per table invite you to join in on the discussion. 

The session will be divided into three rooms, each auditorium focussing on a major topic:

315: "Non-academic careers"

315.1: " Career options and challenges of junior researchers in academia" (BSc, MSc, PhD)

319: "Career options and challenges of senior researchers in academia" (PhD, postdocs, PIs)

More information on the discussion leaders will follow soon.



Non-academic careers


Discussion leaders

  • François Lombard "Teaching Science at school" (University of Geneva)
  • Karl-Heinz Krause "How to create your own company" (University of Geneva)
  • Thomas Marty "University management" (Berinfor)
  • Christophe Grundschober "Working in a big company" (Roche)
  • Julie Deuquet (Nestlé)
  • Mathurin Baquie (Neurix)

Junior Academic careers


Discussion leaders

  • Natacha Turck "Work-Life balance" (University of Geneva)
  • Ekaterina Rostova
  • Melanie Blokesch "Applying for fellowships in CH and abroad" (EPFL)
  • Urs Albrecht (University of Fribourg)
  • Luis Lopez Molina (University of Geneva)

Senior academic careers


Discussion leaders

  • Laurent Keller (University of Lausanne)
  • Monica Gotta (University of Geneva)
  • Dominique Soldati "Career development in academia after postdoc" (University of Geneva)
  • Ramesh Pillai "Career and Family" (EMBL Grenoble)
13:40 – 15:40

Parallel Symposia II


Molecular and Cellular Biosciences

Unravelling more novel paradigms in biology using model organisms


Marja Timmermans (University of Tübingen)

Small RNAs as mobile, morphogen-like signals in plant development


Emily Ann Bayer/Oliver Hobert (Columbia University Medical Center) 

His brain, her brain – C.elegans as model to study sexual dimorphic nervous system development


Veronika Nemčíková Villímová (EPF Lausanne) 

Integrative approach to analyze Trichonympha centriolar cartwheel


Delphine Aymoz (University of Lausanne)

Real-time quantification of protein expression at the single cell level based on dynamic Protein Synthesis Translocation Reporters


Agnès Michel (ETH Zurich)

NGS for "No-pain Genetic Screens": Using transposons and Next-Gen Sequencing to unveil all important yeast loci in one go



Sex hormones and oxytocin/vasopressin signaling: implications for autism spectrum disorder


Sue Carter (Kinsey Institute Indiana)
Oxytocin and human evolution: "What's love got to do with it?"


Markus Heinrichs (University of Freiburg) 

"Social neuropeptides” in the human brain: translational perspectives for new treatment approaches


Jack von Honk (University of Utrecht)

Effects of Steroid and Peptide Hormones on Cognitive and Affective Empathy


Chloé Hegoburu (University of Lausanne)

Optogenetic and electrohysiological dissection of oxytocin in brain circuits underlying social buffering of fear in male and female rats


Christophe Grundschober (Roche) 

Vasopressin antagonism for autism: social behavior rescue in the rat valproate model of autism and clinical translation


Stem Cell Research

In vitro and in vivo applications of stem cell research


Marcel Leist (University of Konstanz)

Use of stem cells to predict human toxicity and to explore the epigenetic basis of drug-induced neurodevelopmental disturbances


 Louis Casteilla (INSERM Toulouse)

Adipose derived stroma/stem cells : from fat to cell therapy


Jakub Zimoch (University of Zurich)

Utilization of adipose-derived cells to bio-engineer skin substitutes that consist of the epidermis, the dermis and the hypodermis



Andrea Coluccio (EPF Lausanne)

The KRABZFP/KAP1 system preserves epigenetic memory in embryonic stem cells


Mathurin Buquie (Neurix)

Human engineered neural tissues as novel model systems for biomedical research


Special Session

Non-academic careers in the Life Sciences


Several speakers will describe why they chose a career outside of academia, how they transitioned from the University to their recent workplace and what challenges they meet in their job.

Fréderic Pailloux (Voisin Life Science Consulting)

Stéphane Bernard (Associate Director Debiopharm International SA)

Adrian Moriette (Biologist Ecoscan SA)

Julie Deuquet (Project Manager Nestlé Institute of Health)

Marie Fischborn (IUCN) 

Davide Staedler (Tibio)

Gioia Althoff (Sophiagenetics)

Each talk will be 10 minutes and be followed by a general Q&A and discussion session at the end.

15:40 – 16:00


16:00 – 16:30

Friedrich-Miescher Award Lecture

Petr Broz (University of Basel)

Sensing the enemy within: innate immune detection of intracellular bacteria

16:30 – 17:20

Plenary Lecture II



John Innes Centre, Norwich

➤ Visit Grieneisen's Lab Page


Patterns within cells, between cells and over tissues: from plant development to robot swarms

17:20 – 19:30



Poster session accompanied by music.

Apero with food and drinks



09:00 – 09:50

Plenary lecture III



Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA

➤ Visit Schroeder's Lab Page


Comparative metabolomics reveals a modular library of signaling molecules in nematodes

09:50 – 10:00

Introducing Matters, the next-gen science journal

Lawrence Rajendran will present Matters, a recently launched innovative journal

10:00 – 10:25


10:30 – 12:30

Parallel Symposia III



Approaches to circumvent channelopathies


Frédéric Becq ( University of Poitiers) 

Structure, dysfunction and correction of F508del-CFTR


Luigi Maiuri (University of Foggia) 

Targeting autophagy to circumvent F508del-CFTR defect


Maud Frieden (University of Geneva)

Ion channels gated by the new STIM1L isoform


Emilia Boiadjieva (University of Zurich)

Cooperation of basolateral epithelial amino acid transporters TAT1 and LAT2 investigated in a double knockout mouse model


Jean-François Denis (University of Geneva)

Connexin40 controls endothelial activation by dampening nuclear translocation of NFκB


Anneline Nansen (Zealand)

Peptide therapeutics - Current status and future directions



Next generation proteomics: enabling biological discoveries


Anne-Claude Gingras (Lunenfeld-Tanenbaum Research Institute, Toronto)

A physical map of the human cell


Robert Beynon (University of Liverpool)

Balancing the books in proteomics: the accountancy of proteostasis


Peter Blattmann (ETH Zürich)

Targeted mass spectrometric analysis of the cellular response to the perturbations of the LXR and SREBP pathway


Michel Schneider (SIB)

Expert curation of proteins in UniProtKB/Swiss-Prot


 Oliver Rinner (Biognosys)

Next-generation proteomics technologies for comprehensive proteome quantification


Laboratory Animal Experimentation

Interdisciplinary 3 R


Matt Leach (Newcastle University)

Pain recognition in small laboratory animals


Paul Flecknell (Newcastle University)

Real and imagined barriers to pain management in rodents


Daniel Brönnimann and Christoph Schneider (Alumni Biomedical Sciences) 

4R: Reduce, Replace, Refine – Rethink?


Beat Riederer (Laboratory Animals Ltd) 

Laboratory Animals, the Journal and the Company


Special session

Tomorrow's PIs- The future of Swiss research


Paloma Ordóñez-Morán (EPF Lausanne) 

Counteracting stem cell traits in colon cancer

Marco Capogrosso (EPF Lausanne)

A theoretical approach to translational neuroscience

Joshua L. Payne (University of Zurich)

Adaptive landscapes of transcriptional regulation

Oscar Vadas (University of Geneva)

Structural insights into phosphoinositide 3-kinases (PI3Ks) regulation

Giulia Pasqual (Mass. Institute of Technology)

In vivo tracking of cell-cell communication in the immune system by enzymatic labeling of ligand-receptor interactions

Marie Barberon  (University of Lausanne)

The endodermis as a checkpoint for nutrients


12:30 – 14:00


Posters with odd numbers are accompanied by the presenter


Lunch-time movie session: BIO•FICTION@Lausanne


Drop in to enjoy a selection of thought-provoking short films blending life sciences and fiction. Presented by the Forum for Genetic Research (SCNAT) in association with the BIO•FICTION Science, Art & Film Festival. Following the films, the debate on Synthetic Biology will be taking place in the same auditory.

14:00 – 16:00

Parallel Symposia IV


Experimental Pharmacology

Pharmacology in the era of Systems Biology


Andrea Califano (Columbia University New York)  

Quantitative and systems pharmacology in the post-genomic era: new approaches to discovering drugs and understanding therapeutic mechanisms


Anna Keppner (University of Lausanne)

Role of the serine protease prostasin (CAP1/Prss8) in DSS-induced chronic colitis


Victor Greiff (ETH Zurich)

A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status


 Chiara Ambühl (University of Geneva)

Biochemical characterization of the putative AMP-activated protein kinase complex of Trypanosoma brucei


Yibo Wu (ETH Zurich)

Systems proteomics and trans-omic data integration illuminate genetic mechanisms linking mitochondrial function and metabolism


Chemical Biology

The interdisciplinary Chemist


Stefan Kubicek (CeMM Vienna)

Transforming cell fate by targeting chromatin modifiers


Christian Hackenberger (FMP Berlin)

Functional protein synthesis


Dimitri Moreau (University of Geneva)

High content compound screen reveal a new modulator of LBPA homeostasis


Jessica Willi (University of Bern)

Oxidized bases in the ribosome's peptidyl transferase center and their effects on translation


Gebhard Thoma (Novartis Basel)

Discovery of a Syk inhibitor active in a collagen-induced arthritis model in rats


SCNAT Forum Genforschung /Forum for Genetic Research

Research breakthroughs and social impact: young scientists debate synthetic biology


Jan Roelof van der Meer (University of Lausanne)

iGEM team 2015 (EPF Lausanne)

Emerging technologies have the potential to offer new solutions for society's challenges but also raise concerns about safety and ethical implications. At this round-table, young scientists from different fields will discuss the possible impact of synthetic biology, a maturing scientific discipline aiming to modify, rebuild and design biological systems. All participants of the meeting are welcome to join the discussion!

Discussion leader Pia Viviani (Science&Cité)

Please find more information on this session here


Special Session

Challenges and opportunities of research funding in Switzerland and Europe


Mauro Dell'Ambrogio (SERI)

The future of Swiss research funding regarding recent changes in the EU-funding scheme for Switzerland


Ayşim Yılmaz (SNF)

Challenges and opportunities for (young) life science researchers in Switzerland


followed by Q&A and discussion round (30 min)

16:00 – 16:30


16:30 – 17:15

Award Session

Lelio Orci Award

Prof. Gisou van der Goot

Poster Awards

Tomorrow's PI awards

17:15 – 18:10

Plenary Lecture IV



Molecular & Cell Biophysics and NanoBioPolymers Lab Graduate Groups in Pharmacology, Physics, Cell & Mol. Biology University of Pennsylvania, Philadelphia, PA, USA

➤ Visit Discher's Lab Page


Cells feel their microenvironment and remodel nuclear structures

18:10 – 18:15

Closing Remarks

Aurélien Roux, meeting chairman (University of Geneva)

Thierry Soldati (President of LS2)