LS² Annual Meeting 2016

Interdisciplinary Sciences

15–16 February, 2016
Amphimax/Amphipôle, Lausanne

Flyer of the meeting

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Final meeting program

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Careers in Science

Meet the discussion leaders of the lunch session "Careers in Science" and decide whom you would like to talk to...

The discussion session is split into three separate rooms: "Junior careers in academia", "Senior careers in academia" and "Non-academic careers".

discussion_leaders_bio.pdf
 
Monday15.02.2016
 

 
09:00 – 09:10

Welcome Address

Aurélien Roux, meeting chairman (University of Geneva)

Thierry Soldati (President of LS2)

 
 
09:10 – 10:00

Plenary Lecture I

 

Lakshminarayanan MAHADEVAN

Harvard University, Department of Physics, Cambridge, USA

➤ Visit Mahadevan's Lab Page

 

Towards a physical basis for morphogenesis

 
 
10:00 – 10:30

COFFEE BREAK and INDUSTRY EXHIBITION

 
 
10:30 – 12:30

Parallel Symposia I

 
 

Molecular and Cellular Biosciences

Unravelling novel paradigms in biology using model organisms

 

Ramesh S. Pillai (EMBL Grenoble)

Genome defense by germline small RNAs

 

Michael O'Connor (University of Minnesota)

Vesicle-mediated steroid hormone secretion in Drosophila melanogaster

 

Rohit Chavan (University of Fribourg)

Liver-derived ketone bodies are necessary for food anticipation

 

Ewald Collins (Harvard Medical School) 

Reduced insulin/IGF-1-signalling implicates extracellular matrix remodelling in longevity

 

Malathi Raman (TAKARA Clontech)

Change the way you think about Cloning….Discover In-Fusion®

 

 

 

Plant Sciences

Plant Molecular and Chemical Biology

 

Dorothea Tholl (Virginia Tech University)

How plant scent makes sense: Studies in Arabidopsis and beyond

 

Jurriaan Ton (University of Sheffield)

Onset and long-term maintenance of plant immune priming

 

Cornelia Eisenach (University of Zurich)

Identification of a vacuolar malate channel required for plant water balance

 

Maite Colinas (University of Geneva)

Balancing of B6 vitamers is essential for plant development and metabolism in Arabidopsis

 

David Heywood (Waters)

Effects of Light Exposure on the Lipid Metabolism of Broccoli Sprouts: An Untargeted, Unbiased Metabolomics Approach

 
 

Microbiology

Microbial division and replication: from biochemistry to molecular biology

 

Patrick Viollier (University of Geneva)
The chlamydial division septum: organisation and regulation

 

Beate Henrichfreise (University of Bonn)
Importance of amidases and peptidoglycan in chlamydial division

 

Ioan Iacovache (University of Bern)

Near-atomic structure of aerolysin mutants reveals a novel protein fold and elucidates its mode of action

 

 Joe Dan Dunn (University of Geneva)

Delineating the immunity functions of reactive oxygen species using Dictyostelium discoideum as a model phagocyte

 

Sophie Martin (University of Lausanne)
Spatio-temporal control of cell division in fission yeast

 
 

Special Session

MSc- what's next?

 

In this session directed at young scientists at the beginning of their career, you can gather information on your career opportunities after having finished with the Master. Several life sciences alumni who have kickstarted their career in Academia, the industry, and non-for profit organisations will answer all your questions in one-to-one discussions. 

 
 
12:30 – 13:40

LUNCH and INDUSTRY EXHIBITION and POSTER SESSION (EVEN NUMBERS)

Posters with even numbers are accompanied by the presenter

 
 
12:40 – 13:30

Careers of women and men in Science

Round table discussion

The lunch session "Careers of women and men in Science" is aimed at providing career support to young researchers at any stage, with a special focus on dual career couples, and women-specific mentoring and fellowships in the life sciences. Several round tables with at least one mentor per table invite you to join in on the discussion. 

The session will be divided into three rooms, each auditorium focussing on a major topic:

315: "Non-academic careers"

315.1: " Career options and challenges of junior researchers in academia" (BSc, MSc, PhD)

319: "Career options and challenges of senior researchers in academia" (PhD, postdocs, PIs)

More information on the discussion leaders will follow soon.

 

 
 

Non-academic careers

 

Discussion leaders

  • François Lombard "Teaching Science at school" (University of Geneva)
  • Karl-Heinz Krause "How to create your own company" (University of Geneva)
  • Thomas Marty "University management" (Berinfor)
  • Christophe Grundschober "Working in a big company" (Roche)
  • Julie Deuquet (Nestlé)
  • Mathurin Baquie (Neurix)
 

Junior Academic careers

 

Discussion leaders

  • Natacha Turck "Work-Life balance" (University of Geneva)
  • Ekaterina Rostova
  • Melanie Blokesch "Applying for fellowships in CH and abroad" (EPFL)
  • Urs Albrecht (University of Fribourg)
  • Luis Lopez Molina (University of Geneva)
 
 

Senior academic careers

 

Discussion leaders

  • Laurent Keller (University of Lausanne)
  • Monica Gotta (University of Geneva)
  • Dominique Soldati "Career development in academia after postdoc" (University of Geneva)
  • Ramesh Pillai "Career and Family" (EMBL Grenoble)
 
 
13:40 – 15:40

Parallel Symposia II

 
 

Molecular and Cellular Biosciences

Unravelling more novel paradigms in biology using model organisms

 

Marja Timmermans (University of Tübingen)

Small RNAs as mobile, morphogen-like signals in plant development

 

Emily Ann Bayer/Oliver Hobert (Columbia University Medical Center) 

His brain, her brain – C.elegans as model to study sexual dimorphic nervous system development

  

Veronika Nemčíková Villímová (EPF Lausanne) 

Integrative approach to analyze Trichonympha centriolar cartwheel

 

Delphine Aymoz (University of Lausanne)

Real-time quantification of protein expression at the single cell level based on dynamic Protein Synthesis Translocation Reporters

 

Agnès Michel (ETH Zurich)

NGS for "No-pain Genetic Screens": Using transposons and Next-Gen Sequencing to unveil all important yeast loci in one go

 

Neurosciences

Sex hormones and oxytocin/vasopressin signaling: implications for autism spectrum disorder

 

Sue Carter (Kinsey Institute Indiana)
Oxytocin and human evolution: "What's love got to do with it?"

 

Markus Heinrichs (University of Freiburg) 

"Social neuropeptides” in the human brain: translational perspectives for new treatment approaches

 

Jack von Honk (University of Utrecht)

Effects of Steroid and Peptide Hormones on Cognitive and Affective Empathy

 

Chloé Hegoburu (University of Lausanne)

Optogenetic and electrohysiological dissection of oxytocin in brain circuits underlying social buffering of fear in male and female rats

 

Christophe Grundschober (Roche) 

Vasopressin antagonism for autism: social behavior rescue in the rat valproate model of autism and clinical translation

 
 

Stem Cell Research

In vitro and in vivo applications of stem cell research

 

Marcel Leist (University of Konstanz)

Use of stem cells to predict human toxicity and to explore the epigenetic basis of drug-induced neurodevelopmental disturbances

 

 Louis Casteilla (INSERM Toulouse)

Adipose derived stroma/stem cells : from fat to cell therapy

 

Jakub Zimoch (University of Zurich)

Utilization of adipose-derived cells to bio-engineer skin substitutes that consist of the epidermis, the dermis and the hypodermis

 

 

Andrea Coluccio (EPF Lausanne)

The KRABZFP/KAP1 system preserves epigenetic memory in embryonic stem cells

 

Mathurin Buquie (Neurix)

Human engineered neural tissues as novel model systems for biomedical research

 
 

Special Session

Non-academic careers in the Life Sciences

 

Several speakers will describe why they chose a career outside of academia, how they transitioned from the University to their recent workplace and what challenges they meet in their job.

Fréderic Pailloux (Voisin Life Science Consulting)

Stéphane Bernard (Associate Director Debiopharm International SA)

Adrian Moriette (Biologist Ecoscan SA)

Julie Deuquet (Project Manager Nestlé Institute of Health)

Marie Fischborn (IUCN) 

Davide Staedler (Tibio)

Gioia Althoff (Sophiagenetics)

Each talk will be 10 minutes and be followed by a general Q&A and discussion session at the end.

 
 
15:40 – 16:00

COFFEE BREAK and INDUSTRY EXHIBITION

 
 
16:00 – 16:30

Friedrich-Miescher Award Lecture

Petr Broz (University of Basel)

Sensing the enemy within: innate immune detection of intracellular bacteria

 
 
16:30 – 17:20

Plenary Lecture II

 

Veronica GRIENEISEN

John Innes Centre, Norwich

➤ Visit Grieneisen's Lab Page

 

Patterns within cells, between cells and over tissues: from plant development to robot swarms

 
 
17:20 – 19:30

POSTER APERO

ALL POSTERS ARE ACCOMPANIED BY THEIR PRESENTER

Poster session accompanied by music.

Apero with food and drinks

 
 

 
Tuesday16.02.2016
 

 
09:00 – 09:50

Plenary lecture III

 

Frank C. SCHROEDER

Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA

➤ Visit Schroeder's Lab Page

 

Comparative metabolomics reveals a modular library of signaling molecules in nematodes

 
 
09:50 – 10:00

Introducing Matters, the next-gen science journal

Lawrence Rajendran will present Matters, a recently launched innovative journal

 
 
10:00 – 10:25

COFFEE BREAK and INDUSTRY EXHIBITION

 
 
10:30 – 12:30

Parallel Symposia III

 
 

Physiology

Approaches to circumvent channelopathies

 

Frédéric Becq ( University of Poitiers) 

Structure, dysfunction and correction of F508del-CFTR

 

Luigi Maiuri (University of Foggia) 

Targeting autophagy to circumvent F508del-CFTR defect

 

Maud Frieden (University of Geneva)

Ion channels gated by the new STIM1L isoform

 

Emilia Boiadjieva (University of Zurich)

Cooperation of basolateral epithelial amino acid transporters TAT1 and LAT2 investigated in a double knockout mouse model

 

Jean-François Denis (University of Geneva)

Connexin40 controls endothelial activation by dampening nuclear translocation of NFκB

 

Anneline Nansen (Zealand)

Peptide therapeutics - Current status and future directions

 

Proteomics

Next generation proteomics: enabling biological discoveries

 

Anne-Claude Gingras (Lunenfeld-Tanenbaum Research Institute, Toronto)

A physical map of the human cell

 

Robert Beynon (University of Liverpool)

Balancing the books in proteomics: the accountancy of proteostasis

 

Peter Blattmann (ETH Zürich)

Targeted mass spectrometric analysis of the cellular response to the perturbations of the LXR and SREBP pathway

 

Michel Schneider (SIB)

Expert curation of proteins in UniProtKB/Swiss-Prot

 

 Oliver Rinner (Biognosys)

Next-generation proteomics technologies for comprehensive proteome quantification

 
 

Laboratory Animal Experimentation

Interdisciplinary 3 R

 

Matt Leach (Newcastle University)

Pain recognition in small laboratory animals

 

Paul Flecknell (Newcastle University)

Real and imagined barriers to pain management in rodents

 

Daniel Brönnimann and Christoph Schneider (Alumni Biomedical Sciences) 

4R: Reduce, Replace, Refine – Rethink?

 

Beat Riederer (Laboratory Animals Ltd) 

Laboratory Animals, the Journal and the Company

 
 

Special session

Tomorrow's PIs- The future of Swiss research

 

Paloma Ordóñez-Morán (EPF Lausanne) 

Counteracting stem cell traits in colon cancer

Marco Capogrosso (EPF Lausanne)

A theoretical approach to translational neuroscience

Joshua L. Payne (University of Zurich)

Adaptive landscapes of transcriptional regulation

Oscar Vadas (University of Geneva)

Structural insights into phosphoinositide 3-kinases (PI3Ks) regulation

Giulia Pasqual (Mass. Institute of Technology)

In vivo tracking of cell-cell communication in the immune system by enzymatic labeling of ligand-receptor interactions

Marie Barberon  (University of Lausanne)

The endodermis as a checkpoint for nutrients

 

 
 
12:30 – 14:00

LUNCH and INDUSTRY EXHIBITION and POSTER SESSION (ODD NUMBERS)

Posters with odd numbers are accompanied by the presenter

 
 

Lunch-time movie session: BIO•FICTION@Lausanne

 

Drop in to enjoy a selection of thought-provoking short films blending life sciences and fiction. Presented by the Forum for Genetic Research (SCNAT) in association with the BIO•FICTION Science, Art & Film Festival. Following the films, the debate on Synthetic Biology will be taking place in the same auditory.

 
14:00 – 16:00

Parallel Symposia IV

 
 

Experimental Pharmacology

Pharmacology in the era of Systems Biology

 

Andrea Califano (Columbia University New York)  

Quantitative and systems pharmacology in the post-genomic era: new approaches to discovering drugs and understanding therapeutic mechanisms

 

Anna Keppner (University of Lausanne)

Role of the serine protease prostasin (CAP1/Prss8) in DSS-induced chronic colitis

 

Victor Greiff (ETH Zurich)

A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status

 

 Chiara Ambühl (University of Geneva)

Biochemical characterization of the putative AMP-activated protein kinase complex of Trypanosoma brucei

 

Yibo Wu (ETH Zurich)

Systems proteomics and trans-omic data integration illuminate genetic mechanisms linking mitochondrial function and metabolism

 

Chemical Biology

The interdisciplinary Chemist

 

Stefan Kubicek (CeMM Vienna)

Transforming cell fate by targeting chromatin modifiers

 

Christian Hackenberger (FMP Berlin)

Functional protein synthesis

 

Dimitri Moreau (University of Geneva)

High content compound screen reveal a new modulator of LBPA homeostasis

 

Jessica Willi (University of Bern)

Oxidized bases in the ribosome's peptidyl transferase center and their effects on translation

 

Gebhard Thoma (Novartis Basel)

Discovery of a Syk inhibitor active in a collagen-induced arthritis model in rats

 
 

SCNAT Forum Genforschung /Forum for Genetic Research

Research breakthroughs and social impact: young scientists debate synthetic biology

 

Jan Roelof van der Meer (University of Lausanne)

iGEM team 2015 (EPF Lausanne)

Emerging technologies have the potential to offer new solutions for society's challenges but also raise concerns about safety and ethical implications. At this round-table, young scientists from different fields will discuss the possible impact of synthetic biology, a maturing scientific discipline aiming to modify, rebuild and design biological systems. All participants of the meeting are welcome to join the discussion!

Discussion leader Pia Viviani (Science&Cité)

Please find more information on this session here

 
 

Special Session

Challenges and opportunities of research funding in Switzerland and Europe

 

Mauro Dell'Ambrogio (SERI)

The future of Swiss research funding regarding recent changes in the EU-funding scheme for Switzerland

 

Ayşim Yılmaz (SNF)

Challenges and opportunities for (young) life science researchers in Switzerland

 

followed by Q&A and discussion round (30 min)

 
 
16:00 – 16:30

COFFEE BREAK and INDUSTRY EXHIBITION

 
 
16:30 – 17:15

Award Session

Lelio Orci Award

Prof. Gisou van der Goot

Poster Awards

Tomorrow's PI awards

 
 
17:15 – 18:10

Plenary Lecture IV

 

Dennis E. DISCHER

Molecular & Cell Biophysics and NanoBioPolymers Lab Graduate Groups in Pharmacology, Physics, Cell & Mol. Biology University of Pennsylvania, Philadelphia, PA, USA

➤ Visit Discher's Lab Page

 

Cells feel their microenvironment and remodel nuclear structures

 
 
18:10 – 18:15

Closing Remarks

Aurélien Roux, meeting chairman (University of Geneva)

Thierry Soldati (President of LS2)